Blood pressure | Top 44 novel treatment findings

Community health workers improve blood pressure control in slum residents

At the end of the two-year follow-up, the proportion of individuals with optimal blood pressure control increased from 26% at baseline to 38%, indicating a significant improvement in hypertension management.

Study published: 2022-07-25

Intensive systolic blood pressure lowering reduces left ventricular hypertrophy risk in older patients with hypertension.

Intensive treatment was associated with a lower risk of new LVH (HR 0.83) and greater regression of mean LV mass index (LVMI) by 0.38 g/m per year. The treatment also showed a favorable effect on cardiovascular outcomes (HR 0.73).

Study published: 2024-03-27

Intensive blood pressure control reduces dementia risk in hypertensive patients

Patients with higher TyG levels had a lower risk of probable dementia, indicating a potential protective effect against cognitive decline in hypertensive individuals.

Study published: 2023-11-08

Isometric exercise reduces blood pressure

The intervention demonstrated good acceptability and adherence, with 87% of completed sessions performed at the correct intensity. Blood pressure reductions were observed at all study time points compared to baseline, indicating a potential for significant systolic blood pressure reduction.

Study published: 2024-02-18

Gene-DASH diet interaction lowers blood pressure in hypertensive individuals.

The study identified significant gene-DASH diet interactions that were associated with lower systolic blood pressure, with specific loci showing consistent effects across different populations. The DASH diet was linked to a reduction in SBP by an average of 0.42 mm Hg in the CHARGE cohort and 0.20 mm Hg in the UK Biobank cohort.

Study published: 2023-11-11

Low diastolic blood pressure increases risk of major cardiovascular events in treated hypertensive patients.

The study found that isolated low diastolic blood pressure (ILDBP) was associated with a 1.32-fold increased risk of major adverse cardiovascular events (MACE) compared to normal diastolic blood pressure levels. In contrast, isolated diastolic hypertension (IDH) did not show a significant increase in MACE risk. The meta-analysis supported the finding that ILDBP is linked to higher MACE risk.

Study published: 2023-08-16

Monitoring systolic blood pressure improves survival in older women

Women with SBP levels between 110 and 130 mmHg had a significantly higher survival probability to age 90, with a 31% absolute survival probability for those on BP medication maintaining this range for 80% of the first 5 years of follow-up.

Study published: 2023-06-29

Motivational interviewing improves hypertension management

The study found a significant improvement in lifestyle patterns among the intervention group, with blood pressure control increasing from 24% at baseline to 48% post-intervention, indicating the effectiveness of motivational interviewing in managing hypertension.

Study published: 2024-04-19

Intensive blood pressure management reduces high systolic blood pressure in acute ischemic stroke patients.

The intensive blood pressure protocol trended towards fewer high SBP protocol violations, although this was not statistically significant, and patient outcomes at 3 months remained unaffected.

Study published: 2023-04-25

Mindfulness training boosts DASH diet adherence

Participants in the MB-BP group showed a significant increase in interoceptive awareness (MAIA score increased by 0.54) and improved DASH diet adherence (DASH score increased by 0.62) compared to the control group after 6 months.

Study published: 2023-05-15

Controlling high blood pressure reduces cognitive decline in adults.

Effective control of hypertension is associated with a reduced risk of cognitive impairment, particularly as diastolic blood pressure is managed.

Study published: 2023-10-22

Proactive blood pressure management improves control in women veterans

After one year, 59% of men and 65% of women achieved blood pressure control, with women showing a 72% greater odds of achieving control compared to men. The study indicates that the first year of hypertension management is crucial for long-term control.

Study published: 2024-04-23

Gut metabolites reduce blood pressure

A clinically relevant reduction in 24-hour systolic blood pressure by 6.1±9.9 mmHg was observed, with significant reductions during both day and night periods. Central SBP was also reduced by 7.2±14.7 mmHg.

Study published: 2022-06-22

Low-volume high-intensity interval exercise reduces cerebrovascular regulation in chronic stroke patients.

The study found that healthy controls showed improved dCA immediately and 30 minutes after HIIT, while individuals post-stroke exhibited lower resting dCA up to 30 minutes after HIIT, indicating a potential challenge in cerebrovascular regulation post-exercise.

Study published: 2023-06-20

Amlodipine and Telmisartan lower blood pressure in Indian adults with hypertension.

The study reported that 70% of patients in Punjab and 76% in Maharashtra achieved controlled blood pressure at the first step of treatment. Overall, there was a significant mean decrease in systolic blood pressure by 16 mmHg in Punjab and 15 mmHg in Maharashtra.

Study published: 2023-08-21

High intensity interval exercise increases blood pressure variability in healthy young adults.

The study found that blood pressure variability was highest during active recovery compared to resting or high-intensity exercise. Additionally, variability increased during HIIE but returned to resting levels post-exercise, indicating a healthy cardiovascular response to exercise.

Study published: 2024-01-30

Slow breathing lowers blood pressure

Significant reductions in systolic blood pressure (SBP) by 2.4 mmHg and diastolic blood pressure (DBP) by 1.6 mmHg were observed after 12 weeks of slow breathing exercises. Participants with baseline SBP over 120 mmHg and/or DBP over 90 mmHg experienced further reductions in SBP by 10.3 mmHg and DBP by 3.8 mmHg.

Study published: 2022-08-31

Antihypertensive medications improve blood pressure control in hypertensive patients.

The study found that 72.5% of participants adhered to antihypertensive medications, but only 23.4% achieved controlled blood pressure. Factors such as dietary adherence and chronic kidney disease were associated with better adherence, while alcohol consumption was inversely related to blood pressure control.

Study published: 2024-01-12

Antihypertensive drugs lower blood pressure in patients with hypertension.

The study found that antihypertensive drugs effectively lowered blood pressure, with significant reductions in systolic and diastolic BP observed across various baseline BP values, ages, and patient characteristics. More intense treatment resulted in greater reductions compared to less intense treatment and placebo.

Study published: 2021-02-23

Antihypertensive medications lower stroke risk in older patients after stroke.

The study highlights the importance of adhering to clinical practice guidelines for antihypertensive treatment post-stroke, which can significantly reduce the risk of recurrent strokes and improve overall patient outcomes. However, it notes that adherence rates are below the quality standard of 85%.

Study published: 2023-02-16

Short interval high intensity exercise improves cerebral blood flow in healthy adults.

MCAv remained above baseline during the HIIE session and returned to near baseline values 30 minutes after exercise, indicating a maintained cerebral blood flow during the exercise.

Study published: 2021-05-11

Blood pressure-lowering medications improve health outcomes in adults with hypertension

Improved adherence to blood pressure-lowering medications is associated with better blood pressure control, reduced risk of complications such as stroke and heart disease, and overall improved health outcomes for individuals with hypertension.

Study published: 2024-05-29

Pharmacogenomic testing improves hypertension control

The study found that pharmacogenomic testing led to significant improvements in systolic blood pressure (SBP) and diastolic blood pressure (DBP) after one year, particularly in patients with actionable genotypes. SBP improved by an average of 14.8 mmHg and DBP by 8.4 mmHg in those with uncontrolled hypertension and actionable genotypes.

Study published: 2021-04-06

Gene expression in fat reduces blood pressure in Cushing's syndrome patients.

Identification of a unique gene expression signature in VAT that correlates with hypertension in Cushing's syndrome patients. The study suggests that local tissue effects can have long-term impacts on blood pressure regulation even after surgical intervention.

Study published: 2023-03-03

Endovascular thrombectomy reduces stroke severity in patients with acute ischemic stroke.

58.9% of patients had a good discharge disposition, indicating successful recovery post-EVT.

Study published: 2023-12-07

Sodium reduction lowers blood pressure

Significant reduction in blood pressure levels among hypertensive patients was observed with sodium intake reduction, highlighting its effectiveness as a management strategy.

Study published: 2023-09-18

Acupuncture stabilizes blood pressure during surgery

The study aims to demonstrate that acupuncture can significantly reduce the differences between the highest and lowest mean blood pressures during surgery, thereby improving hemodynamic stability and reducing the incidence of hypotension and hypertension.

Study published: 2024-07-26

Antihypertensive drugs improve recovery after ischemic stroke in patients with high blood pressure.

The study found that genetic predisposition to higher blood pressure was associated with a lower probability of favorable functional outcomes after ischemic stroke. ACEI and CCB were significantly associated with improved outcomes, indicating their potential benefit in stroke management.

Study published: 2023-04-10

Caloric restriction does not lower blood pressure in obese adults.

The findings indicate that individuals on caloric restriction do not experience a significant benefit in lowering blood pressure by reducing sodium intake, suggesting that dietary sodium reduction may not be necessary for this population.

Study published: 2021-01-02

Community health worker intervention reduces hypertension

The intervention group showed a significant reduction in mean systolic blood pressure (SBP) by 8.4 mm Hg and diastolic blood pressure (DBP) by 5.2 mm Hg, with 62.2% achieving controlled BP compared to 25.8% in the usual care group.

Study published: 2023-10-21

Mobile health interventions improve blood pressure control in vulnerable populations.

Some mHealth interventions demonstrated a significant reduction in blood pressure among participants, particularly those that incorporated care teams, indicating potential effectiveness in improving hypertension control in vulnerable groups.

Study published: 2023-04-10

Centhaquine boosts cardiac output in shock

Significant increases in stroke volume, cardiac output, and mean arterial pressure were observed after treatment, indicating improved hemodynamic status and potential for better tissue perfusion.

Study published: 2024-03-29

Telehealth reduces blood pressure effectively

Both treatment arms showed a reduction in 24-hour systolic BP, with the dietitian telehealth arm demonstrating greater improvements in sleep systolic BP, sleep diastolic BP, and self-reported physical activity. The dietitian arm also showed a trend towards greater weight loss and improved healthy eating index scores, although these were not statistically significant.

Study published: 2022-04-03

GLP-1 receptor agonists lower blood pressure

GLP-1RAs modestly reduced systolic blood pressure (SBP) compared to placebo, with significant reductions noted for semaglutide, liraglutide, dulaglutide, and exenatide. Only exenatide showed a significant reduction in diastolic blood pressure (DBP).

Study published: 2024-01-30

Digital app reduces hypertension effectively

Patients using the app experienced significant reductions in morning home systolic blood pressure, with a decrease of 4.7 mmHg at week 12 and 6.1 mmHg at week 24, which were greater than those observed in the control group. The app showed effectiveness across various demographics, including older adults and those on medication.

Study published: 2024-03-04

Mindfulness reduces blood pressure and stress

Significant reductions in both systolic and diastolic blood pressure were observed in the intervention group, along with substantial improvements in positive and negative stress scores compared to the control group.

Study published: 2023-12-08

Monitoring central blood pressure reduces cardiovascular events in patients without hypertension.

Patients with isolated central hypertension experienced increased cardiovascular events, indicating the importance of monitoring CBP.

Study published: 2023-02-07

Long-term blood pressure lowering reduces cardiovascular disease risk in middle-aged Europeans.

A predicted 16.9% decrease in morbidity for a 5 mmHg decrease in SBP, 30.8% for a 10 mmHg decrease, and 56.2% for a 22.7 mmHg decrease, indicating significant potential health benefits from lowering blood pressure.

Study published: 2021-02-09

Management of hypertension improves blood pressure control in older patients.

The study found that older patients and those with hypertension exhibited greater seasonal variations in blood pressure, suggesting that tailored treatment approaches may improve management outcomes during different seasons.

Study published: 2021-11-16

Metformin reduces blood pressure and hypertension

The analysis indicated that metformin use significantly reduced both systolic blood pressure (SBP) and diastolic blood pressure (DBP), with a notable reduction in hypertension risk. Specifically, a genetically proxied reduction equivalent to 6.75 mmol/mol in HbA1c was associated with a decrease in SBP (Beta=-1.05, P <0.001) and DBP (Beta=-0.51, P=0.096).

Study published: 2023-04-17

COVID-19 disrupted hypertension management

Despite the disruptions caused by the COVID-19 pandemic, the study found that blood pressure screening rates remained stable in certain demographics, such as older age groups and patients with learning disabilities or care home status. There was a recovery in the percentage of patients treated to target after initial declines during the pandemic.

Study published: 2023-07-31

The Blood Pressure Postpartum Trial reduces cardiovascular risks in women with hypertensive disorders.

The trial aims to provide evidence on effective follow-up and lifestyle changes that could mitigate cardiovascular risks in postpartum women with a history of HDP.

Study published: 2023-04-25

Monitoring heart rate improves outcomes in autonomic dysreflexia patients

Improved understanding of heart rate changes associated with autonomic dysreflexia, leading to better monitoring and management strategies during procedures that may trigger these episodes.

Study published: 2021-04-06

Household air pollution raises blood pressure

The study found moderate increases in systolic blood pressure and decreases in diastolic blood pressure with increased exposure to particulate matter, black carbon, and carbon monoxide, although these associations were not statistically significant.

Study published: 2023-01-26